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Image Search Results
Journal: American Journal of Physiology - Heart and Circulatory Physiology
Article Title: Reduced pericyte and tight junction coverage in old diabetic rats are associated with hyperglycemia-induced cerebrovascular pericyte dysfunction
doi: 10.1152/ajpheart.00726.2020
Figure Lengend Snippet: Validation of HBMVPs and identification of PAs. A: representative images of the expression of α-SMA-, PDGFR-β-, DES-, and CD13-positive HBMVPs. Images were captured with an Eclipse 55i fluorescence microscope connected with a DS-FiL1 color camera (Nikon, Melville, NY) at the magnification of ×850. B: representative image of isolated PAs covered with α-SMA- and PDGFR-β-positive-stained pericytes. Yellow arrows point to α-SMA- and PDGFR-β-positive pericytes. Red and green arrows point to α-SMA- and PDGFR-β-positive pericytes, respectively. The slides were imaged with a Nikon C2+ confocal head mounted on an Eclipse Ti2 inverted microscope (Nikon) using a ×60 oil immersion objective (total magnification of ×1,320). DES, desmin; HBMVPs, human brain microvascular pericytes; PAs, parenchymal arterioles; PDGFR-β, platelet-derived growth factor receptor β; α-SMA, α-smooth muscle actin.
Article Snippet: The slides were imaged with a
Techniques: Expressing, Fluorescence, Microscopy, Isolation, Staining, Inverted Microscopy, Derivative Assay